Custom-made transcriptional biosensors for metabolic engineering

Custom Made Mold Brachytherapy

Engineering prokaryotic transcriptional activators as metabolite biosensors in yeast.

Whole-cell biocatalysts have proven a tractable path toward sustainable production of bulk and fine chemicals. Yet the screening of libraries of cellular designs to identify best-performing biocatalysts is most often a low-throughput endeavor. For this reason, the development of biosensors enabling real-time monitoring of production has attracted attention. Here we applied systematic engineerin...

A custom-made head pointer for children.

Severely physically disabled adults and children may be able to use a head pointer to access an augmentative communication system or to participate in activities. This paper describes how to make and fit a thermoplastic head pointer and how to train a child to use it.

Two-stage pricing for custom-made products

A commonly observed two-stage pricing strategy for a custom-made product involves a prepurchase entry fee for a potential consumer and a purchase price if he decides to buy the product. We solve and compare two settings: In the first, the firm does not commit in advance to the second-stage price and in the second, the firm does. We show that without a commitment mechanism, the two price points ...

Custom-made healthcare – An experimental investigation

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